Hôpital Saint-Louis AP-HP – Projet Lymphome T
USA and France
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Hôpital Saint-Louis AP-HP – Projet Lymphome T
Current mission
USA and France
- Since
14/06/2023
It is clear that the immune profile of the tumor in numerous solid tumors strongly influences their prognosis. The development of immunotherapies represents a clear revolution in patient care. In this context, the analysis of the spatial tumor-immune microenvironments (TIME), is of major interest for the knowledge of cancer and the discovery of new innovative therapies. T-cell lymphomas constitute a broad spectrum of hemopathies for which conventional therapies have limited effectiveness. To date, TIME in T-cell lymphomas remains poorly defined. We propose to uncovering it, taking advantage of state-of-the-art tools in spatial analysis such as multiplex immunofluorescence and CO-Detection by indEXing (CODEX) (simultaneous detection of 5-50 proteins) and spatial transcriptomics (simultaneous detection of several thousand transcripts). Mapping the TIME in T-cell lymphomas will lead to identifying rational tumor subtypes and immunological targets for innovative therapeutic strategies.
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View the website
https://hopital-saintlouis.aphp.fr/
The copyright in the music as well as the rights in the recording of “Hand” are the property of Moshe Almachias - © 2014 and are only made available for private, non-commercial use. This work may not be copied, distributed or broadcast without the copyright owner's prior consent. All rights reserved.
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Testimonial
You are contributing to our understanding of the immune microenvironment in order to develop innovative, effective treatments for T lymphoma.
By Manuela Klapouszczak - Directrice at Hôpital Saint-Louis AP-HP – Projet Lymphome T
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Institut Imagine des maladies génétiques
Past mission
France
- Since
14/02/2018
One of the leading European centers for research, care and teaching in genetic diseases, the Institute Imagine 's staff includes 850 of the best physicians, researchers and healthcare professionals housed in an innovative new building designed to generate synergy, located on the Necker Hospital Campus in Paris. This unprecedented continuum of expertise available in close proximity to patients allows Imagine to make discoveries for patients. The approximately 9,000 genetic diseases inventoried affect 35 million patients in Europe and 3 million in France, where 30,000 new cases are recorded every year. Close to 60% of children are undiagnosed following consultation for a genetic condition. Curative treatments have yet to be discovered for 90% of genetic diseases. The challenge of this major public health issue is twofold: diagnose and cure.
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View the website
http://www.institutimagine.org/en/
The copyright in the music as well as the rights in the recording of “Hand” are the property of Moshe Almachias - © 2014 and are only made available for private, non-commercial use. This work may not be copied, distributed or broadcast without the copyright owner's prior consent. All rights reserved.
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Testimonial
Your support is precious : it is a real encouragement to families and our teams who are fighting together to understand and treat genetic diseases
By Professeur Stanislas Lyonnet - Director at Institut Imagine des maladies génétiques
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Solving Kid’s Cancer (SKC), The Bibi Fund
Past mission
worldwide
- Since
27/07/2017
SKC is an independent and nonprofit organization which invests in the highest-impact childhood cancer research projects without any ties to any particular research institution or hospital.
SKC works across borders and in collaboration with other like-minded nonprofit organizations.
SKC has a world-renowned scientific board and a proven track record in finding, funding and advocating for innovative research projects, which create more novel and less toxic treatment options for children with cancer and ultimately save lives.
100% of all donations go to research.
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View the website
http://solvingkidscancer.org/
The copyright in the music as well as the rights in the recording of “Hand” are the property of Moshe Almachias - © 2014 and are only made available for private, non-commercial use. This work may not be copied, distributed or broadcast without the copyright owner's prior consent. All rights reserved.
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Testimonial
SKC is committed to improving survivorship of the deadliest childhood cancers and your gift will make an impact toward that goal in Bibi's honor
By Scott Kennedy - Co-founder at Solving Kid’s Cancer (SKC), The Bibi Fund
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DNDi
Past mission
Switzerland
- Since
01/01/2010
Drugs for neglected Diseases initiative (DNDi) is a patient-needs driven, non-for-profit research and development organisation founded in 2003 by seven organisations from around the world:
- The Oswaldo Cruz Foundation from Brazil
- The Indian Council for medical research
- The Kenya Medical Research institute
- The Ministry of Health of Malaysia
- France’s Pasteur institute
- Médecins sans Frontières
- The UNDP/worldBank who’s special program for Research and Training in Tropical Diseases.
DNDi develops safe, effective, and affordable new treatments for diseases such as malaria, sleeping sickness (human African trypanosomiasis), leishmaniasis, and Chagas disease that afflict millions of the world’s poorest people. DNDi’s primary objective is to deliver six to eight new treatments by 2014 and to establish a strong R&D portfolio for these diseases.
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View the website
http://www.dndi.org/
The copyright in the music as well as the rights in the recording of “Hand” are the property of Moshe Almachias - © 2014 and are only made available for private, non-commercial use. This work may not be copied, distributed or broadcast without the copyright owner's prior consent. All rights reserved.
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Testimonial
Unbelievably, children with neglected diseases are even worse‐off than adults when it comes to the availability and efficacy of treatments, and today, your donation shows that we share the same concern regarding their specific treatment needs.
By Dr Luis Pizarro, MD, MSc, MBA - Executive Director at DNDi
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ICM
Current mission
France
- Since
01/01/2010
ICM is a unique medical organisation that carries out research on the prevention and treatment of brain and spinal cord disorders. Innovative in both concept and design, ICM is the sole organization of its kind that brings patients and top medical professionals from around the world under one roof, thereby eliminating the delay between research and its application. Additionally, ICM implements a revolutionary model of multi-disciplinary research that unites the top minds from a variety of medical fields to develop new treatments. ICM is also one of the few private foundations to be recognized as of public usefulness, and thus is able to benefit from the financial support of both public institutions and private funds.
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View the website
http://icm-institute.org/fr/
The copyright in the music as well as the rights in the recording of “Hand” are the property of Moshe Almachias - © 2014 and are only made available for private, non-commercial use. This work may not be copied, distributed or broadcast without the copyright owner's prior consent. All rights reserved.
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Testimonial
Thanks to your support, we now have 826 experts at the Institut du Cerveau, and in 2023 we will have recruited two very promising new research teams
By Pr Gérard Saillant - President at ICM
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ARSEP Foundation
Past mission
France
- Since
01/01/2011
ARSEP Foundation was created in1969 to finance Multiple Sclerosis (MS) research in France and worldwide. Research is a beacon of hope for patients.
- Multiple Sclerosis affects up to 2 million people in the world.
- ⅔ of the patients are women.
- It’s the principal cause of acquired neurological handicap in adults. It usually starts between the ages of 20 and 40. ARSEP also informs the general public about scientific, medical and therapeutic advances.
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View the website
http://www.arsep.org/
The copyright in the music as well as the rights in the recording of “Hand” are the property of Moshe Almachias - © 2014 and are only made available for private, non-commercial use. This work may not be copied, distributed or broadcast without the copyright owner's prior consent. All rights reserved.
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Testimonial
Ensure fully and with exigency the totality of the missions to advance, day by day, towards the long awaited treatment.
By Jean Frédéric de LEUSSE - General Manager at ARSEP Foundation
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Our missions for a better future
38 missions since 28, January 2009